In space, as was first noted in the ad campaign for the movie Alien, no one can hear you scream. What prompts that screaming in the Alien franchise and other space opera sci-fi is typically terror...
But more mundane issues make real-life astronauts want to scream.
Space, when done with people living together in close quarters, stinks.
We humans are incredibly demanding because of our hunger and thirst—and the messy, odoriferous products of our satiety. Humans are the reason the space shuttle needs toilets.
Showers are also too tricky to deal with out there. So it's no surprise that the interior of your average spaceship quickly winds up smelling very, very bad. Think of a car ride with three immature guys for whom "pull my finger" is considered a droll example of classic wit. Now imagine spending a week in the car with the windows rolled up.